On 2 November 1675, the queen consort Mariana of Austria founded the "Town of Our Lady of Candelaria of Medellín". Today Medellín is the second-largest city in Colombia and the capital of the departme.. Read more »nt of Antioquia. In February 2013, the Urban Land Institute chose Medellín as the most innovative city in the world due to its recent advances in politics, education and social development. In the same year, Medellín was announced as the preferred corporate business destination in South America.The most recent survey on the global status of the Smart Cities by Indra Systems catalogs Medellín as one of the best cities to live in South America, sharing first place with Santiago de Chile, and alongside Barcelona and Lisbon in Europe.Medellín won the Lee Kuan Yew World City Prize 2016. The award seeks to recognize and celebrate efforts in furthering innovation in urban solutions and sustainable urban development